Development of atmospheric pressure ionization ion mobility spectrometry and ion mobility spectrometry mass spectrometry
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منابع مشابه
DETECTION AND MEASUREMENT OF ACETONE IN THE BREATH OF DIABETICS BY ION MOBILITY SPECTROMETRY METHOD
Background: The ion mobility spectrometry (IMS) is an analytical technique that is widely used due to its high sensitivity and speed for the detection of ionized molecules in gas phase and under atmospheric pressure. Breath analysis is a new method for obtaining information about person's clinical conditions that is considered by researchers. Human exhaled air contains a variety of components s...
متن کاملElectrospray ionization high-resolution ion mobility spectrometry-mass spectrometry.
A hybrid atmospheric pressure ion mobility spectrometer is described which exhibits resolving power approaching the diffusion limit for singly and multiply charged ions (over 200 for the most favorable case). Using an electrospray ionization source and a downstream quadrupole mass spectrometer with electron multiplier as detector, this ESI-IMS-MS instrument demonstrates the potential of IMS for...
متن کاملSeparation of sodiated isobaric disaccharides and trisaccharides using electrospray ionization-atmospheric pressure ion mobility-time of flight mass spectrometry.
A series of isobaric disaccharide-alditols, four derived from O-linked glycoproteins, and select trisaccharides were rapidly resolved using tandem high resolution atmospheric pressure ion-mobility time-of-flight mass spectrometry. Electrospray ionization was used to create the gas-phase sodium adducts of each carbohydrate. Using this technique it was possible to separate up to three isobaric di...
متن کاملApplication of Ion Mobility Spectrometry for Determination of Morphine in Human Urine
In this study, a rapid, simple and sensitive ion mobility spectrometry (IMS) method with corona discharge as ionization source was described for the morphine determination in human urine. Morphine was extracted and purified from urine samples using solid phase extraction procedure with C18 column. It can offer the clean extracts which no extra peaks were observed in IMS. Under operating experim...
متن کاملAtmospheric pressure matrix-assisted laser desorption/ionization with analysis by ion mobility time-of-flight mass spectrometry.
The use of an atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) source was employed with an atmospheric pressure ion mobility spectrometer (APIMS) and an orthogonal acceleration reflector time-of-flight mass spectrometer (TOFMS) to analyze dipeptide and biogenic amine mixtures from a liquid glycerol 2,5-dihydroxybenzoic acid (DHB) matrix. Improved sensitivities were ob...
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تاریخ انتشار 2011